Anterior cruciate ligament reconstruction with a porcine xenograft: a serologic, histologic, and biomechanical study in primates.

@article{Stone2007AnteriorCL,
  title={Anterior cruciate ligament reconstruction with a porcine xenograft: a serologic, histologic, and biomechanical study in primates.},
  author={Kevin R. Stone and Ann W. Walgenbach and Thomas J. Turek and Damon L Somers and Winston N. Wicomb and Uri Galili},
  journal={Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association},
  year={2007},
  volume={23 4},
  pages={411-9}
}
PURPOSE This study proposes treatment methods to provide a mechanically competent, immunocompatible, and sterile porcine graft for human knee ligament reconstruction. METHODS The anterior cruciate ligament (ACL) was reconstructed by using treated porcine patellar tendon grafts or controls of untreated porcine grafts or allografts in 20 rhesus monkeys. Animals were stratified into 2-, 6-, and 12-month postreconstruction cohorts. Serologic and histologic assessments were performed to evaluate… CONTINUE READING

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