Anterior boundaries of Hox gene expression in mesoderm-derived structures correlate with the linear gene order along the chromosome.
@article{Dressler1989AnteriorBO, title={Anterior boundaries of Hox gene expression in mesoderm-derived structures correlate with the linear gene order along the chromosome.}, author={G. Dressler and P. Gruss}, journal={Differentiation; research in biological diversity}, year={1989}, volume={41 3}, pages={ 193-201 } }
The developmental expression patterns of four genes, Hox 1.1, Hox 1.2, Hox 1.3 and Hox 3.1, were examined by in situ hybridization to serial embryonic sections. The three genes of the Hox 1 cluster, used in this study, map to adjacent positions along chromosome 6, whereas the Hox 3.1 gene maps to the Hox 3 cluster on chromosome 15. The anterior expression limits in segmented mesoderm varied among the four genes examined. Interestingly, a linear correlation exists between the position of the… CONTINUE READING
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