Anterior/Posterior Competitive Deactivation/Activation Dichotomy in the Human Hippocampus as Revealed by a 3D Navigation Task

@inproceedings{Duarte2014AnteriorPosteriorCD,
  title={Anterior/Posterior Competitive Deactivation/Activation Dichotomy in the Human Hippocampus as Revealed by a 3D Navigation Task},
  author={Isabel Catarina Duarte and Carlos Ferreira and Jo{\~a}o Marques and Miguel Castelo-Branco},
  booktitle={PloS one},
  year={2014}
}
Anterior/posterior long axis specialization is thought to underlie the organization of the hippocampus. However it remains unclear whether antagonistic mechanisms differentially modulate processing of spatial information within the hippocampus. We used fMRI and a virtual reality 3D paradigm to study encoding and retrieval of spatial memory during active visuospatial navigation, requiring positional encoding and retrieval of object landmarks during the path. Both encoding and retrieval elicited… CONTINUE READING

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