Antenatal, intrapartum and neonatal risk factors for cerebral palsy in children in podlaskie province

Abstract

The aim of this study was to identify antenatal, intrapartum and neonatal risk factors for cerebral palsy (CP) among babies in Podlaskie Province. Antenatal, intrapartum, and neonatal events were compared between 345 children with CP and 360 controls in a retrospective case-control method. Antenatal, intrapartum and neonatal factors were expressed as odds ratios and 95% confidence intervals. Factors associated with an increased risk of CP identified as antenatal and intrapartum risk factors were: abruptio placenta, pre-labour rupture of membranes, prematurity, preterm labour, cesarean section and low birth weight (< 2500 gram). Respiratory distress syndrome, prolonged ventilation, septicemia, meningitis, hyperbilirubinemia, neonatal seizures, and severe cranial ultrasound abnormality were associated with an increased risk of CP in the neonatal period. In the logistic regression models prematurity and asphyxia were significantly associated with an increased risk of CP. For all CP children born between 2000–2006 we found significant increase in the number of tetraplegic and extrapyramidale CP types compared to CP children born between 1983–1999. Our findings confirm that several antenatal, intrapartum and neonatal risk factors for CP in babies are responsible for the etiology of CP.

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Cite this paper

@inproceedings{mzgowego2011AntenatalIA, title={Antenatal, intrapartum and neonatal risk factors for cerebral palsy in children in podlaskie province}, author={Czynniki ryzyka m{\'o}zgowego and wojew{\'o}dztwa podlaskiego and Wojciech Kułak and Wojciech Sobaniec and Bożena Okurowska-Zawada and Dorota Sienkiewicz and Grażyna Paszko-Patej}, year={2011} }