Antenatal Seroprevalence of Herpes Simplex Virus Type 2 (HSV-2) in Canadian Women: HSV-2 Prevalence Increases Throughout the Reproductive Years

  title={Antenatal Seroprevalence of Herpes Simplex Virus Type 2 (HSV-2) in Canadian Women: HSV-2 Prevalence Increases Throughout the Reproductive Years},
  author={David Patrick and Meena Dawar and Darrel A. Cook and Mel Krajden and Helen Ng and Michael L. Rekart},
  journal={Sexually Transmitted Diseases},
Background Thisstudy sought to provide the first population estimates of herpes simplex type2 (HSV-2) seroprevalence inCanada. Goal Tomeasure the antenatal seroprevalence of HSV-2 antibodies in reproductive agewomen. StudyDesign An anonymous unlinked seroprevalence study usedstored sera collected from pregnant women in British Columbia during 1999.Randomized sampling within age strata selected a total of 1215 subjects, ages15 to 44 years. Serologic testing used the Gull Meridian Test… 
Prevalence and Risk Factors for Herpes Simplex Virus Type 2 Infection Among Pregnant Women in Israel
A relatively low seroprevalence of HSV-2 infection in a demographically mixed group of pregnant women in Israel is documented, and the role of high-risk sexual behavior in the spread of the infection has been reconfirmed.
Seroprevalence of Herpes Simplex Virus type-2 (HSV-2) among pregnant women who participated in a national HIV surveillance activity in Haiti
The prevalence of HSV-2 is relatively high among pregnant women in Haiti and public health interventions to increase access to HSV/HIV screening in antenatal services are warranted.
The changing epidemiology of HSV-1 and HSV-2 and implications for serological testing.
  • W. Lafferty
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    Herpes : the journal of the IHMF
  • 2002
The advent of highly sensitive virological tests has confirmed that HSV-2 is the most common cause of genital ulceration in the developing world, and patients with a high standard of living may escape oral herpes simplex virus infection in childhood.
Seroprevalence, Type-Specific of Herpes Simplex Virus and Associated Risk Factors among Women of Child Bearing Age in Kogi State, Nigeria
The prevalence of the HSV-1 andHSV-2 infections was high among asymptomatic healthy women of childbearing age in Kogi state, Nigeria and efforts should be made to increase the awareness of HSV infection among the child bearing populace.
Regional Distribution of Antibodies to Herpes Simplex Virus Type 1 (HSV-1) and HSV-2 in Men and Women in Ontario, Canada
Both types of HSV antibodies appeared to be acquired earlier among women under prenatal care than among men and women not under antenatal care, and were more prevalent among people in northern Ontario than elsewhere.
Herpes Simplex Virus Seroprevalence and Risk Factors in 2 Canadian Sexually Transmitted Disease Clinics
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Seroprevalence of HSV-1 and HSV-2 antibodies in Canadian women screened for enrolment in a herpes simplex virus vaccine trial
The likelihood of participants being seropositive to HSV-1 and to HSv-2 was found to increase with age and to positively correlate with the population of the city in which they resided, and hypotheses are proposed to account for differences in racial seropositivity.
Prevalence of Chlamydia trachomatis and herpes simplex virus type 2: Results from the 2009 to 2011 Canadian Health Measures Survey.
This study is the first in Canada to report laboratory-confirmed prevalence of chlamydia and HSV-2 using a nationally representative sample, and results suggest that most infected people are unaware of their status.
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Seroepidemiology of Herpes Simplex Type 2 in Pregnant Women in Belgium
The results obtained with the control sera indicate a high of the Focus ELISA, as well as a capacity to discriminate between HSV-1/HSV-2 infection, which raises the question of the possible benefit of a specific preventive program in pregnant women.


Is sexual transmission an important pattern for herpes simplex type 2 virus seroconversion in the Spanish general population?
Seroprevalence rates found in the group of females of childbearing age and in the youngest population indicate that perinatal viral shedding is the main source of HSV‐2 seroconversion in the Spanish population.
Seroprevalence of herpes simplex virus type 2 antibodies in an STD clinic in Paris
The very high HSV-2 seroprevalence of patients with STDs, only a few of whom have a history of genital herpes, underlines the need for detection and counselling for these patients.
Herpes simplex type 2 infection in a cohort aged 21 years.
HSV-2 seropositivity did not appear to be a sensitive marker for high risk sexual activity in this young population, and may be because a critical mass of HSV-1 carriers has not accumulated among potential partners by age 21 years.
Herpes simplex virus type 2 in the United States, 1976 to 1994.
Improvements in the prevention of HSV-2 infection are needed, particularly since genital ulcers may facilitate the transmission of the human immunodeficiency virus.
Correlates of herpes simplex virus seroprevalence among women attending a sexually transmitted disease clinic.
BothHSV-1 and HSV-2 seropositivity were related directly to age and were higher among African Americans than whites, and public health interventions to prevent HSv-2 infection should target teenagers.
An epidemiologic study of herpes simplex virus type 1 and 2 infection in Japan based on type-specific serological assays
Primary genital HSV-2 infection, with its higher frequency of clinical manifestations, will become a greater burden to the public health in Japan.
[Herpes simplex virus type 1 and 2 in Switzerland].
The results indicate the significance of herpes simplex virus type 2 infections in Switzerland, especially in view of progress in the development of vaccines against HSV infections.
Seroprevalence of herpes simplex virus types 1 and 2 and cytomegalovirus in adolescents.
The data demonstrating a high prevalence of infection during adolescence suggest that immunization for HSV, HSV-2, and CMV may need to occur in childhood.
Analysis of herpes simplex virus 1 and 2 infection in women with high risk sexual behaviour in Mexico.
This is the first assessment of HSV infection in Mexico and may be useful for the development and application of control and preventive measures among the prostitute population at risk of acquiring and transmitting human immunodeficiency virus (HIV) and other STD.
Seroprevalence of herpes simplex virus-type 2 in African-American college women.
It is indicated that for young African-American college women, the risk of being infected with HSV-2 is high even with only one lifetime partner, and Behavioral strategies focused on decreasing the number of sexual partners are not likely to be sufficient in preventing the spread of HSV -2 infection.