Antenatal Seroprevalence of Herpes Simplex Virus Type 2 (HSV-2) in Canadian Women: HSV-2 Prevalence Increases Throughout the Reproductive Years

@article{Patrick2001AntenatalSO,
  title={Antenatal Seroprevalence of Herpes Simplex Virus Type 2 (HSV-2) in Canadian Women: HSV-2 Prevalence Increases Throughout the Reproductive Years},
  author={David Patrick and Meena Dawar and Darrel A. Cook and Mel Krajden and Helen Ng and Michael L. Rekart},
  journal={Sexually Transmitted Diseases},
  year={2001},
  volume={28},
  pages={424-428}
}
Background Thisstudy sought to provide the first population estimates of herpes simplex type2 (HSV-2) seroprevalence inCanada. Goal Tomeasure the antenatal seroprevalence of HSV-2 antibodies in reproductive agewomen. StudyDesign An anonymous unlinked seroprevalence study usedstored sera collected from pregnant women in British Columbia during 1999.Randomized sampling within age strata selected a total of 1215 subjects, ages15 to 44 years. Serologic testing used the Gull Meridian Test… 
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Significant association was found between HSV 2 seroprevalence and education levels, residence, smoking and animal exposure, and presence of pregnancy in women with HSV-2 latent infection was a risk factor for development of BOH.
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The results obtained with the control sera indicate a high of the Focus ELISA, as well as a capacity to discriminate between HSV-1/HSV-2 infection, which raises the question of the possible benefit of a specific preventive program in pregnant women.
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