Antenatal Corticosteroids Increase Fetal, But Not Postnatal, Pulmonary Blood Flow in Sheep

  title={Antenatal Corticosteroids Increase Fetal, But Not Postnatal, Pulmonary Blood Flow in Sheep},
  author={Kelly J. Crossley and Colin John Morley and Beth J Allison and Peter G Davis and Graeme Roger Polglase and Megan J. Wallace and Valerie A. Zahra and Stuart Brian Hooper},
  journal={Pediatric Research},
The lungs of very preterm infants have immature airways and gas exchange structures and are usually surfactant deficient. Antenatal corticosteroids are commonly used to enhance fetal lung maturation in preterm infants, but little is known of their effects on pulmonary blood flow (PBF) before and immediately after birth. Our aim was to determine the effects of antenatal betamethasone on PBF before birth and during the postnatal transition in very preterm lambs. Antenatal betamethasone treatment… CONTINUE READING


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