Antenatal Betamethasone for Women at Risk for Late Preterm Delivery.

@article{GyamfiBannerman2016AntenatalBF,
  title={Antenatal Betamethasone for Women at Risk for Late Preterm Delivery.},
  author={C. Gyamfi‐Bannerman and E. Thom and S. Blackwell and A. Tita and U. Reddy and G. Saade and D. Rouse and D. Mckenna and E. Clark and J. Thorp and E. Chien and A. Peaceman and R. Gibbs and G. Swamy and M. Norton and B. Casey and S. Caritis and J. Tolosa and Y. Sorokin and J. P. Vandorsten and L. Jain},
  journal={The New England journal of medicine},
  year={2016},
  volume={374 14},
  pages={
          1311-20
        }
}
BACKGROUND Infants who are born at 34 to 36 weeks of gestation (late preterm) are at greater risk for adverse respiratory and other outcomes than those born at 37 weeks of gestation or later. It is not known whether betamethasone administered to women at risk for late preterm delivery decreases the risks of neonatal morbidities. METHODS We conducted a multicenter, randomized trial involving women with a singleton pregnancy at 34 weeks 0 days to 36 weeks 5 days of gestation who were at high… Expand
Antenatal Betamethasone for Women at Risk for Late Preterm Delivery.
TLDR
It was definitively concluded that administration of betamethasone to women at risk for late preterm delivery significantly reduces the rate of neonatal respiratory complications. Expand
Does antenatal corticosteroid therapy improve neonatal outcomes in late preterm birth?
  • Nuran Üstün, M. Hocaoglu, A. Turgut, S. Arslanoglu, F. Ovalı
  • Medicine
  • The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
  • 2020
TLDR
Administration of ACS during the late preterm period decreased neonatal respiratory complications, however, increased the rate of hypoglycemia. Expand
Antenatal betamethasone for women at risk for late preterm delivery reduces the rate of neonatal respiratory complications
TLDR
This study confirmed that provision of antenatal corticosteroids (ANCS) for threatened late preterm delivery decreases the rate of neonatal respiratory complications, and it is prudent to follow recommendations of the American Academy of Pediatrics in terms of screening for hypoglycaemia in this at-risk population, regardless of maternal medications. Expand
Antenatal corticosteroids in the late preterm period for growth-restricted pregnancies.
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Administration of antenatal corticosteroids in the late preterm period for pregnancies with growth restriction did not significantly decrease the need for respiratory support in newborns at the authors' institution, and the rate of neonatal hypoglycemia increased after exposure to antenatal Corticosteroid. Expand
The role of prenatal steroids at 34–36 weeks of gestation
TLDR
It is argued that steroids should not be used in the context of late preterm delivery until evidence of long-term safety is available, and both the science of glucocorticoids in pregnancy and thescience of clinical trials are considered. Expand
Antenatal dexamethasone for early preterm birth in low-resource countries
TLDR
Antenatal dexamethasone treatment of women at risk of early preterm birth in low-resource countries resulted in a significantly lower risk of neonatal death and any baby death, and no increase in possible maternal bacterial infection. Expand
The association between antenatal corticosteroid use in late-preterm and early-term pregnancy and nonreassuring fetal status
This study aimed to compare perinatal outcomes, including nonreassuring fetal status, according to antenatal corticosteroid therapy (ACT) use during late-preterm and early-term pregnancies. This wasExpand
Amniocentesis compared with antenatal corticosteroids prior to early term scheduled cesarean delivery
  • Kelly B Zafman, N. Fox
  • Medicine
  • The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
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TLDR
In women undergoing scheduled cesarean delivery between 36 and 38 6/7 weeks, administration of antenatal corticosteroids is associated with similar neonatal outcomes compared to amniocentesis, and this supports the current notion that outcomes are similar with ACS compared to Amnocentesis for late preterm and early term deliveries. Expand
Preterm Prelabor Rupture of Membranes: Outcomes with Expectant Management until 34 versus 35 Weeks.
TLDR
There is no difference in composite neonatal morbidity in pregnancies with preterm PROM managed with expectant management until 35 weeks as compared with immediate delivery at 34 weeks, and Expectant management is associated with a decreased length of NICU admission but increased short-term infectious morbidity. Expand
Antenatal dexamethasone use and respiratory distress in late preterm infants: results from first Vietnamese matched cohort study
  • Tran Tuan Hung Ho, Quang Vinh Truong, Thi Kim Anh Nguyen, M. Le, Vu Quoc Huy Nguyen
  • Medicine
  • BMC Pregnancy and Childbirth
  • 2021
TLDR
Administration of antenatal dexamethasone to women at risk forLate preterm birth could help to lower the proportion of respiratory distress in late preterm infants. Expand
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