Antaxia-telangiectasia mutated gene polymorphisms and susceptibility to chromosomal damage among polycyclic aromatic hydrocarbons exposed workers.

@article{Wang2009AntaxiatelangiectasiaMG,
  title={Antaxia-telangiectasia mutated gene polymorphisms and susceptibility to chromosomal damage among polycyclic aromatic hydrocarbons exposed workers.},
  author={Yadong Wang and Huawei Duan and Y. Sophia Dai and P. O. Bin and Juan Cheng and Zufei Pan and Chuanfeng Huang and Shuguang Leng and Yuxin Zheng},
  journal={The Science of the total environment},
  year={2009},
  volume={407 8},
  pages={2615-20}
}
The aim was to explore the relationship between the ataxia-telangiectasia mutated (ATM) gene polymorphisms and susceptibility to cytokinesis-block micronucleus among workers exposed to polycyclic aromatic hydrocarbons (PAH). Blood and urine samples of 140 PAH-exposed workers and 66 non-PAH-exposed workers were collected. Seven tagging single nucleotide polymorphisms in ATM gene were selected by pariwise r(2) method and minor allele frequency cutoff of 0.05 from Chinese genotype data in HapMap… CONTINUE READING