Antagonistic roles of Wnt5 and the Drl receptor in patterning the Drosophila antennal lobe

Abstract

Numerous studies have shown that ingrowing olfactory axons exert powerful inductive influences on olfactory map development. From an overexpression screen, we have identified wnt5 as a potent organizer of the olfactory map in Drosophila melanogaster. Loss of wnt5 resulted in severe derangement of the glomerular pattern, whereas overexpression of wnt5… (More)
DOI: 10.1038/nn1993

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