Antagonistic Roles for H3K36me3 and H3K27me3 in the Cold-Induced Epigenetic Switch at Arabidopsis FLC

@inproceedings{Yang2014AntagonisticRF,
  title={Antagonistic Roles for H3K36me3 and H3K27me3 in the Cold-Induced Epigenetic Switch at Arabidopsis FLC},
  author={Hongchun Yang and Martin Howard and Caroline Dean},
  booktitle={Current Biology},
  year={2014}
}
Posttranslational modifications of histone tails are an important factor regulating chromatin structure and gene expression. Epigenetic memory systems have been predicted to involve mutually exclusive histone modifications that, through positive feedback mechanisms, generate bistable states. How the states are interconverted is not understood, and whether the histone modifications are sufficient for epigenetic memory is still greatly debated. We have exploited the process of vernalization, the… CONTINUE READING
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