Antagonism of the discriminative effects of ethylketazocine, cyclazocine, and nalorphine in macaques

@article{Young2004AntagonismOT,
  title={Antagonism of the discriminative effects of ethylketazocine, cyclazocine, and nalorphine in macaques},
  author={A. Young and K. R. Stephens},
  journal={Psychopharmacology},
  year={2004},
  volume={84},
  pages={356-361}
}
  • A. Young, K. R. Stephens
  • Published 2004
  • Medicine
  • Psychopharmacology
  • Abstractdl-Ethylketazocine (EKC, 0.01 mg/kg) and saline were established as discriminative stimuli for food-maintained responding in macaque monkeys. Thirty consecutive presses on a right or left lever were reinforced with food, contingent on whether EKC or saline were administered before the session. For tests of antagonism, naltrexone, or UM 979 [(l)-5,9-alpha-dimethyl-2-(3-furylmethyl)-2′-hydroxy-6,7-benzomorphan] was administered concomitantly with EKC,dl-cyclazocine, or nalorphine. Both… CONTINUE READING
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