Antagonism of the anticoagulant effect of warfarin caused by the use of Commiphora molmol as a herbal medication: a case report

  title={Antagonism of the anticoagulant effect of warfarin caused by the use of Commiphora molmol as a herbal medication: a case report},
  author={Saud Al Faraj},
  journal={Annals of Tropical Medicine \& Parasitology},
  pages={219 - 220}
  • S. Al Faraj
  • Published 2005
  • Medicine
  • Annals of Tropical Medicine & Parasitology
The shrub or small tree Commiphora molmol, known in Arabic as murrah (‘the bitter’) and in English as myrrh, is often used as a herbal remedy in the Arab world, usually as an aqueous extract of the boiled gummy root, taken by mouth. The commonest traditional use is for the treatment of diabetes mellitus. There is some evidence, from rats given a petroleum extract of the plant resin, that the herb can help alleviate some of the problems of diabetes, by reducing appetite and food intake (S. Al… Expand
TREATING MALARIA and PARASITE DISORDERS with NATURAL MEDICINE Phytotherapy Review & Commentary by Kerry Bone , FNIMH , FNHAA
  • 2007
Myrrh has been used as a medicinal herb for thousands of years. It is mentioned several times in the Bible, in writings as old as Psalms and the Song of Solomon, and of course it is well known as oneExpand
Commiphora myrrha (Nees) Engl. resin extracts induce phase-I cytochrome P450 2C8, 2C9, 2C19, and 3A4 isoenzyme expressions in human hepatocellular carcinoma (HepG2) cells
Both sonicated and boiled C. myrrha aqueous extracts modulate CYP 2C8, 2C9, 2 C19, and 3A4 gene expression at clinically-relevant concentrations regardless of preparation methods, and the up-regulation of CYP mRNA expression levels induced by both boiled and sonicated C.myrrha extracts was confirmed at the CYP protein expression levels. Expand
A Review of Potential Harmful Interactions between Anticoagulant/Antiplatelet Agents and Chinese Herbal Medicines
Conventional anticoagulants and antiplatelet drugs were documented to have harmful interactions with some commonly used single entity CHMs, specifically danshen, dong quai, ginger, ginkgo, licorice, and turmeric. Expand
Interactions between Herbs and Conventional Drugs: Overview of the Clinical Data
  • A. Izzo
  • Medicine
  • Medical Principles and Practice
  • 2012
An overview of the clinical evidence of interactions between herbal and conventional medicines is provided and healthcare professionals should remain vigilant for potential interactions between herbs and prescribed drugs, especially when drugs with a narrow therapeutic index are used. Expand
Critical evaluation of causality assessment of herb–drug interactions in patients
Assessment of the severity of adverse drug reactions (ADRs) due to herb–drug interactions (HDI) in patients taking herbs and prescribed medications found HDI occurred in patients resulting in clinical ADRs with different severity. Expand
Cytotoxicity in MCF-7 and MDA-MB-231 Breast Cancer Cells, withoutHarming MCF-10A Healthy Cells
Globally, breast cancer in women has become a major issue of concern, especially with treatment methods that are harmful to the patients. This research involved the trisodium citrate dihydrate (TSCD)Expand
Warfarin and food, herbal or dietary supplement interactions: A systematic review
An updated overview on the safety of concurrent use of food, herbal or dietary supplement and warfarin is presented. Expand
Herb–Drug Interactions: Worlds Intersect with the Patient at the Center
Reliable herb–drug information is needed, including open and respectful discussion with patients, and Cohen’s kappa found no agreement between any interaction checker and case report corpus. Expand