Antagonism of leukotriene B4 receptors does not limit canine myocardial infarct size.

Abstract

Injection of leukotriene (LT)B4 (0.1-3 micrograms/kg i.v.) in normal anesthetized dogs produced dose-related leukopenia that was accompanied by arterial hypotension and tachycardia at higher tested doses. LTD4 (0.1-3 micrograms/kg i.v.), in contrast, increased arterial blood pressure, lowered cardiac rate and produced little change in arterial blood… (More)

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Cite this paper

@article{Hahn1990AntagonismOL, title={Antagonism of leukotriene B4 receptors does not limit canine myocardial infarct size.}, author={Richard A. Hahn and Brian R. MacDonald and Patricia J. Simpson and Brian D Potts and C J Parli}, journal={The Journal of pharmacology and experimental therapeutics}, year={1990}, volume={253 1}, pages={58-66} }