Antagonism of cefamandole by cefoxitin in routine disk susceptibility tests.


Cefoxitin was found to antagonize cefamandole in standardized disk diffusion susceptibility tests. This antagonism increased as the distance between the two disks decreased, and was most frequently observed in tests with cephalothin-resistant Enterobacteriaceae. It occurred in tests with 68 of 98 (69%) cephalothin-resistant isolates, one of six (17… (More)


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