Antagonism of blockade produced by atracurium or vecuronium with low doses of neostigmine.

@article{Jones1988AntagonismOB,
  title={Antagonism of blockade produced by atracurium or vecuronium with low doses of neostigmine.},
  author={Jacqueline E Jones and Christy Parker and Jennifer Hunter},
  journal={British journal of anaesthesia},
  year={1988},
  volume={61 5},
  pages={560-4}
}
Neostigmine 1.25 mg or 0.625 mg was used to antagonize neuromuscular blockade produced by either atracurium 0.5 mg kg-1 or vecuronium 0.1 mg kg-1 in four groups of patients (n = 45) when the first EMG response of the train-of-four (A') had recovered to 10% of control (A). The time for A'/A and the train-of-four ratio (D'/A') to reach 70% was recorded. It was found that, after both atracurium and vecuronium, neostigmine 1.25 mg considerably accelerated recovery and, when compared with previous… CONTINUE READING

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Neostigmine in the antagonism of the action of atracurium.

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