Antagonism by taurine of pressure-induced tremor in the guinea pig.


The tremorogenic effect of high pressure was antagonized in guinea pigs by intravenous treatment with taurine in doses of 250 and 500 mg/kg. Also pretreatment with 250 mg/kg taurine suppressed tremor development as evidenced by increased threshold and decreased amplitude. It is hypothesized that antagonism of pressure-induced tremor by taurine may be related to changes in membrane calcium transport.


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@article{Gilman1984AntagonismBT, title={Antagonism by taurine of pressure-induced tremor in the guinea pig.}, author={Steven C. Gilman and John M. Hallenbeck and Margaret J Ackerman and Mary E. Bradley}, journal={Journal of applied physiology: respiratory, environmental and exercise physiology}, year={1984}, volume={57 5}, pages={1409-11} }