Antagonism between bicuculline and GABA in the cat brain.
@article{Curtis1971AntagonismBB, title={Antagonism between bicuculline and GABA in the cat brain.}, author={David Roderick Curtis and Arthur W. Duggan and Dominik Felix and Graham A. R. Johnston and H. Mclennan}, journal={Brain research}, year={1971}, volume={33 1}, pages={ 57-73 } }
359 Citations
Bicuculline, an antagonist of GABA and synaptic inhibition in the spinal cord of the cat.
- BiologyBrain research
- 1971
The effect of bicuculline upon synaptic inhibition in the cerebral and cerebellar corticles of the cat.
- BiologyBrain research
- 1971
Antagonism between bicuculline, strychnine, and picrotoxin and depressant amino-acids in the rat nervous system.
- BiologyComparative and general pharmacology
- 1972
The effectiveness of bicuculline as an antagonist of GABA and visually evoked inhibition in the cat's striate cortex.
- BiologyThe Journal of physiology
- 1975
The present results support the view that GABA is an inhibitory transmitter in the visual cortex by suggesting that the iontophoretic application of bicuculline by blocking or reducing the inhibitory input moves the balance between the inputs in favour of the excitatory input.
Decreased sensitivity of cerebellar nuclei neurons to GABA and taurine: effects of long-term inferior olive destruction in the rat
- BiologyNeuroscience Research
- 1991
Neurotransmitters in the Vestibular Commissural System of the Cat
- BiologyAnnals of the New York Academy of Sciences
- 1992
It is concluded that vestibular type 1 neurons are controlled by GABAergic and glycinergic but not serotoninergic neurons, and commissural inhibition is activated by the GABAA receptor, but not by the GABAB receptor.
The effect of GABA and its antagonists on midbrain periaqueductal gray neurons in the rat
- BiologyPain
- 1990
Neurotransmitters regulating vestibular commissural inhibition in the cat.
- BiologyActa oto-laryngologica. Supplementum
- 1991
It is concluded that vestibular type 1 neurons are controlled by GABAergic and glycinergic neurons, and that the commissural inhibition is activated by the GABAA receptor, but not by the GABAB receptor.
References
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Bicuculline, an antagonist of GABA and synaptic inhibition in the spinal cord of the cat.
- BiologyBrain research
- 1971
The effect of bicuculline upon synaptic inhibition in the cerebral and cerebellar corticles of the cat.
- BiologyBrain research
- 1971
Iontophoretic studies in Deiters' nucleus of the inhibitory actions of GABA and related amino acids and the interactions of strychnine and picrotoxin.
- BiologyBrain research
- 1971
Depression of cerebellar Purkinje cells by microiontophoretic application of GABA and related amino acids.
- BiologyBrain research
- 1970
Amino‐acid induced depression of cortical neurones
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- 1970
It is concluded that strychnine can specifically and competitively antagonize the effect of glycine on cortical neurones and prolong the time‐course of onset of GABA and 5‐HT depression.
ANTIDROMIC AND TRANS-SYNAPTIC ACTIVATION OF DEITERS' NEURONES INDUCED FROM THE SPINAL CORD.
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In view of the fast time course of the action potential and of rarity of the possible recurrent inhibition, it was postulated that Deiters' neurones would be grouped with the fast type of lumbosacral motoneurones.
THE EXCITATION AND DEPRESSION OF MAMMALIAN CORTICAL NEURONES BY AMINO ACIDS.
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- 1964
Amino acids related to L-glutamic and gamma-amino-n-butyric acid have been administered electrophoretically, and by pressure ejection, into the extraneuronal environment of single neurones in the…
Excitatory and inhibitory processes acting upon individual Purkinje cells of the cerebellum in cats
- BiologyThe Journal of physiology
- 1956
It would seem highly desirable to be able to elucidate the role of the unique system of basket cells (B-cells) with dendritic receptors in the molecular layer (and possibly elsewhere) and efferent axons (B.e.) in the cerebellar afferent system.
Acetylcholine sensitivity of cerebellar neurones in the cat
- Biology, ChemistryThe Journal of physiology
- 1966
1. Cholinomimetics, acetylcholine antagonists and some other compounds of pharmacological interest were administered electrophoretically near neurones within the vermal cerebellar cortex of…