Ant Colony Optimisation for Exploring Logical Gene-Gene Associations in Genome Wide Association Studies

@inproceedings{Sapin2013AntCO,
  title={Ant Colony Optimisation for Exploring Logical Gene-Gene Associations in Genome Wide Association Studies},
  author={Emmanuel Sapin and Ed Keedwell and Timothy M. Frayling},
  booktitle={IWBBIO},
  year={2013}
}
In this paper a search for the logical variants of gene-gene interactions in genome-wide association study (GWAS) data using ant colony optimisation is proposed. The method based on stochastic algorithms is tested on a large established database from the Wellcome Trust Case Control Consortium and is shown to discover logical operations between combinations of single nucleotide polymorphisms that can discriminate Type II diabetes. A variety of logical combinations are explored and the best… CONTINUE READING

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