Anoxia or oxygen and glucose deprivation in SH-SY5Y cells: a step closer to the unraveling of neuroglobin and cytoglobin functions.

@article{Fordel2007AnoxiaOO,
  title={Anoxia or oxygen and glucose deprivation in SH-SY5Y cells: a step closer to the unraveling of neuroglobin and cytoglobin functions.},
  author={Elke Fordel and Liesbet Thijs and Wim Martinet and Dorien Schrijvers and L. Moens and Sylvia Dewilde},
  journal={Gene},
  year={2007},
  volume={398 1-2},
  pages={114-22}
}
Several studies support the hypothesis that neuroglobin and cytoglobin play a protective role against cell death when cellular oxygen supply is critical. Although the underlying molecular mechanisms are unknown, previous reports suggest that this protection can be realised by the fact that they act as ROS scavengers. In this study, expression of neuroglobin and cytoglobin was evaluated in a human neuroblastoma cell line (SH-SY5Y) under conditions of anoxia or oxygen and glucose deprivation (OGD… CONTINUE READING

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