Anosognosia in Alzheimer disease: Disconnection between memory and self-related brain networks.

@article{Perrotin2015AnosognosiaIA,
  title={Anosognosia in Alzheimer disease: Disconnection between memory and self-related brain networks.},
  author={Audrey Perrotin and B{\'e}atrice Desgranges and Brigitte Landeau and Florence M{\'e}zenge and Renaud La Joie and St{\'e}phanie Egret and Alice P{\'e}lerin and Vincent de la Sayette and Francis Eustache and Ga{\"e}l Ch{\'e}telat},
  journal={Annals of neurology},
  year={2015},
  volume={78 3},
  pages={477-86}
}
OBJECTIVE Impaired awareness is a common symptom in many mental disorders including Alzheimer disease (AD). This study aims at improving our understanding of the neural mechanisms underlying anosognosia of memory deficits in AD by combining measures of regional brain metabolism (resting state fluorodeoxyglucose positron emission tomography [FDG-PET]) and intrinsic connectivity (resting state functional magnetic resonance imaging [fMRI]). METHODS Twenty-three patients diagnosed with probable… CONTINUE READING
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