Anorexia nervosa

  title={Anorexia nervosa},
  author={Janet Treasure and Stephan Zipfel and Nadia Micali and Tracey Wade and Eric Stice and Ang{\'e}lica M. Claudino and Ulrike Schmidt and Guido K. Frank and Cynthia M. Bulik and Elisabet Wentz},
  journal={Nature Reviews Disease Primers},
Anorexia nervosa (AN) is a psychiatric condition characterized by severe weight loss and secondary problems associated with malnutrition. AN predominantly develops in adolescence in the peripubertal period. Without early effective treatment, the course is protracted with physical, psychological and social morbidity and high mortality. Despite these effects, patients are noted to value the beliefs and behaviours that contribute to their illness rather than regarding them as problematic, which… 

Anorexia nervosa: Outpatient treatment and medical management

The core aim of this opinion review is to provide the knowledge base needed for performing safe outpatient treatment of AN, including how to assess and manage the medical risks of AN and how to decide when transition to inpatient care is indicated.

Sudden gains in the outpatient treatment of anorexia nervosa: A process‐outcome study

This study investigated whether SGs were associated with changes in BMI, eating disorder symptomology, general psychopathology, and psychosocial impairment between baseline and 6, 12, and 24 months follow-up.

Anorexia nervosa in adolescents.

This review of anorexia nervosa in adolescents provides an overview of the presentation, aetiology and treatment of this disorder, with a particular focus on the assessment and management of physical health risks, including refeeding syndrome.

Treatment of Anorexia Nervosa—New Evidence-Based Guidelines

The new guideline is presented and changes, in comparison with the original guideline published in 2011, are discussed and the German guideline is compared to current international evidence-based guidelines for eating disorders.

Body shape in inpatients with severe anorexia nervosa

Findings provide support to the effectiveness of hospitalization in improving body shape concerns and body avoidance, but not body checking; baseline bodyshape concerns (especially body checking) impacted on clinical improvement.

Anorexia nervosa: 30-year outcome

This long-term follow-up study reflects the course of adolescent-onset anorexia nervosa and has shown a favourable outcome regarding mortality and full symptom recovery, however, one in five had a chronic eating disorder.

Pseudo Bartter Syndrome in anorexia nervosa.

The case of a patient with a binge-eating/purging subtype of anorexia nervosa, whose purges consisted in diuretic abuse, emphasizes the importance of being familiarized with the non-psychiatric manifestations of eating disorders, so they may be rapidly recognized and managed.

Illness Perception in Adolescent Patients With Anorexia: Does It Play a Role in socio-Emotional and Academic Adjustment?

It was showed that anorexia patients’ illness perceptions were related to socio-emotional and academic adjustment, while emotional representation was associated with a worse emotional and social adjustment.

High levels of physical activity in female adolescents with anorexia nervosa: medical and psychopathological correlates

Assessing the possible associations between levels of physical activity (PA) and clinical features, endocrinological data and psychopathological traits in a sample of 244 female adolescents hospitalised for AN suggests that high levels ofPhysical activity in acute AN associate with worst clinical conditions at admission, especially in terms of endocrineological and medical features.



Antidepressants for anorexia nervosa.

Four placebo-controlled trials did not find evidence that antidepressants improved weight gain, eating disorder or associated psychopathology, and future studies testing safer and more tolerable antidepressants in larger, well designed trials are needed to provide guidance for clinical practice.

Inpatient Treatment for Anorexia Nervosa: A Systematic Review of Randomized Controlled Trials

Most add-on treatments during the acute inpatient phase of AN treatment are not effective in increasing weight recovery, and long-term follow-up studies after the acute treatment phase are needed to make evidence-based recommendations.

Long-term follow-up of adolescent onset anorexia nervosa in northern Sweden

Results from the study implied that one should stimulate the patients’ social contacts and their sense of self-efficacy in their recovery- process, and that patients with initial high levels of perfectionism may need more complex treatment strategies.

Epidemiology and course of anorexia nervosa in the community.

The authors found a substantially higher lifetime prevalence and incidence of anorexia nervosa than reported in previous studies, most of which were based on treated cases.

Anorexia nervosa in young men: A cohort study.

Male gender in AN--on a group level--suggests a good psychiatric prognosis and some differences between male patients with AN and the male population without AN concerning social background, capacity to support oneself, and living with partner and child are suggested.

Compulsivity in anorexia nervosa: a transdiagnostic concept

Viewing compulsivity as a transdiagnostic concept, seen in various manifestations across disorders, may help delineate the mechanisms responsible for the persistence of anorexia nervosa, and aid treatment development.

Should amenorrhea be a diagnostic criterion for anorexia nervosa?

It is suggested that one option is to describe amenorrhea in DSM-V as a frequent occurrence among individuals with AN that may provide important information about clinical severity, but should not be maintained as a core diagnostic feature.

Temperament-based treatment for anorexia nervosa.

  • W. KayeC. Wierenga I. Eisler
  • Psychology
    European eating disorders review : the journal of the Eating Disorders Association
  • 2015
This model integrates the development of AN-focused constructive coping strategies with carer-focused strategies to manage temperament traits that contribute to AN symptomatology and is consistent with the recent Novel Interventions for Mental Disorders initiative.

Anorexia Nervosa: Outcome and Prognostic Factors after 20 Years

There was a general consistency between the follow- up at 20 years and that previously conducted five years after admission, although with a few individual patients there were serious prognostic errors at the earlier follow-up.

Adolescent-onset anorexia nervosa: 18-year outcome.

The 18-year outcome of teenage-onset anorexia nervosa is favourable in respect of mortality and persisting eating disorder.