Anomalous dynamics of the endoplasmic reticulum network.

@article{Speckner2018AnomalousDO,
  title={Anomalous dynamics of the endoplasmic reticulum network.},
  author={Konstantin Speckner and Lorenz Stadler and Matthias Weiss},
  journal={Physical review. E},
  year={2018},
  volume={98 1-1},
  pages={
          012406
        }
}
Large portions of the endoplasmic reticulum (ER) in eukaryotic cells are organized as dynamic networks whose segments are connected by three-way junctions. Here we show that ER junctions move subdiffusively with signatures of fractional Brownian motion and a strong dependence on the cytoskeleton's integrity: The time-averaged mean square displacement scales as 〈r^{2}(τ)〉_{t}∼τ^{α} with α≈0.5 in untreated cells and α≈0.3 when disrupting microtubules, with successive steps being anticorrelated in… 
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