Annular repair using high-density collagen gel: a rat-tail in vivo model.

  title={Annular repair using high-density collagen gel: a rat-tail in vivo model.},
  author={Peter Grunert and Brandon H Borde and Katherine Deline Hudson and Michael R Macielak and Lawrence J. Bonassar and Roger H{\"a}rtl},
  volume={39 3},
STUDY DESIGN Animal in vivo study. OBJECTIVE To test the capability of high-density collagen gel to repair annular defects. SUMMARY OF BACKGROUND DATA Annular defects are associated with spontaneous disc herniations and disc degeneration, which can lead to significant morbidity. Persistent annular defects after surgical discectomies can increase reherniation rates. Several synthetic and biological materials have been developed for annular repair. This is the first study to test an… CONTINUE READING
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Riboflavin and collagen: New crosslinking methods to tailor the stiffness of hydrogels

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