Annotating functional RNAs in genomes using Infernal.

  title={Annotating functional RNAs in genomes using Infernal.},
  author={Eric P. Nawrocki},
  journal={Methods in molecular biology},
Many different types of functional non-coding RNAs participate in a wide range of important cellular functions but the large majority of these RNAs are not routinely annotated in published genomes. Several programs have been developed for identifying RNAs, including specific tools tailored to a particular RNA family as well as more general ones designed to work for any family. Many of these tools utilize covariance models (CMs), statistical models of the conserved sequence, and structure of an… CONTINUE READING
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