Annexin V relocates to the platelet cytoskeleton upon activation and binds to a specific isoform of actin.

Abstract

We have previously reported that stimulation of platelets causes a relocation of annexin V to the cytoplasmic side of the plasma membrane where it associates with actin. This study examined the association of annexin V with the platelet cytoskeleton and its binding to actin, following both physiological activation with thrombin and Ca2+ -ionophore… (More)

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