Annexin-I overexpression is associated with tumour progression and independently predicts inferior disease-specific and metastasis-free survival in urinary bladder urothelial carcinoma.

@article{Li2010AnnexinIOI,
  title={Annexin-I overexpression is associated with tumour progression and independently predicts inferior disease-specific and metastasis-free survival in urinary bladder urothelial carcinoma.},
  author={C. Li and Kun-Hung Shen and Li-Chien Huang and H. Lisa Huang and Yuhui Wang and Ting-Feng Wu},
  journal={Pathology},
  year={2010},
  volume={42 1},
  pages={43-9}
}
AIMS In our previous studies, comparative proteomics and immunohistochemistry (IHC) demonstrated that annexin-I (ANXA1) is up-regulated in high grade urinary bladder urothelial carcinoma (UBUC) as compared to non-high grade carcinomas. However, the small sample size prohibited further correlation of ANXA1 expression to tumour progression. Therefore, in the present study, 81 primary localised UBUC specimens of various grades and primary tumour (pT) status were examined for ANXA1 expression to… CONTINUE READING