Annexin A2 recognises a specific region in the 3'-UTR of its cognate messenger RNA.

@article{Holls2006AnnexinAR,
  title={Annexin A2 recognises a specific region in the 3'-UTR of its cognate messenger RNA.},
  author={Hanne Holl{\aa}s and Ingvild Aukrust and Stine Grimmer and Elin Strand and Torgeir Flatmark and Anni Vedeler},
  journal={Biochimica et biophysica acta},
  year={2006},
  volume={1763 11},
  pages={1325-34}
}
Annexin A2 is a multifunctional Ca(2+)- and lipid-binding protein. We previously showed that a distinct pool of cellular Annexin A2 associates with mRNP complexes or polysomes associated with the cytoskeleton. Here we report in vitro and in vivo experiments showing that Annexin A2 present in this subset of mRNP complexes interacts with its cognate mRNA and c-myc mRNA, but not with beta(2)-microglobulin mRNA translated on membrane-bound polysomes. The protein recognises sequence elements within… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 22 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 53 references

The compartmentalization of polysomes into free

  • A. Vedeler, I. F. Pryme, J. E. Hesketh
  • cytoskeletal-bound and membrane-bound populations…
  • 2006
Highly Influential
5 Excerpts

Similar Papers

Loading similar papers…