Annexin A2 is regulated by ovarian cancer-peritoneal cell interactions and promotes metastasis

@inproceedings{Lokman2013AnnexinAI,
  title={Annexin A2 is regulated by ovarian cancer-peritoneal cell interactions and promotes metastasis},
  author={Noor A. Lokman and Alison S. F. Elder and Miranda Ween and Carmen E. Pyragius and Peter Hoffmann and Martin K. Oehler and Carmela Ricciardelli},
  booktitle={Oncotarget},
  year={2013}
}
Our recent research identified the protein annexin A2 to be regulated by ovarian cancer-peritoneal cell interactions. This study investigated the role of annexin A2 in ovarian cancer metastasis and its potential utility as a novel therapeutic target, using in vitro and in vivo ovarian cancer models. Annexin A2 expression was examined by qRT-PCR and western blotting in ovarian cancer cell lines and immunohistochemistry in serous ovarian carcinoma tissues. Annexin A2 siRNAs were used to evaluate… CONTINUE READING

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