Annexin A2 is implicated in multi-drug-resistance in gastric cancer through p38MAPK and AKT pathway.

@article{Zhang2014AnnexinAI,
  title={Annexin A2 is implicated in multi-drug-resistance in gastric cancer through p38MAPK and AKT pathway.},
  author={Zhidong Zhang and Yang Li and Qi Fan and B Zhao and Bi-bo Tan and X Zhao},
  journal={Neoplasma},
  year={2014},
  volume={61 6},
  pages={
          627-37
        }
}
Studies have shown that Annexin A2 (ANXA2) is related with tumor proliferation, apoptosis, differentiation, invasion, migration, and drug resistance. The purpose of this study was to investigate the role and its mechanisms of ANXA2 in multi-drug-resistance (MDR) in gastric cancer. ANXA2 expression in both gastric cancer tissues and cell lines were detected by quantitative real-time PCR (RT-qPCR) and Western blotting. The cell proliferation was measured by SRB assay. The pool of siRNA against… Expand
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