Ankle-brachial index and extent of atherosclerosis in patients from the Middle East (the AGATHA-ME study): a cross-sectional multicenter study.

Abstract

To assess the extent of atherothrombosis and the use of the ankle-brachial index (ABI) in populations from the Middle East, we conducted a multicenter study similar to AGATHA (a Global Atherothrombosis Assessment), AGATHA-ME, which included 1341 patients from 18 centers from 5 countries (United Arab Emirates, Kuwait, Qatar, Bahrain, and Oman). Patients were assigned to 2 groups: the with-disease and at-risk groups. Abnormal ABI (< or =0.9) was seen in 31.5% of at-risk patients and 28.2% of with-disease patients. Patients with peripheral arterial disease had the highest frequency of abnormal ABI (77.6%), with 97.8 negative predictive value. The AGATHA-ME study confirms that atherothrombosis disease often occurs at more than 1 site. The ABI is related to the risk factor profile and to the site and extent of atherothrombosis. Gender and diabetes mellitus are associated with the worst parameters.

DOI: 10.1177/0003319708321585

Cite this paper

@article{ElMenyar2009AnklebrachialIA, title={Ankle-brachial index and extent of atherosclerosis in patients from the Middle East (the AGATHA-ME study): a cross-sectional multicenter study.}, author={Ayman El-Menyar and Haitham Amin and Ibrahim Rashdan and Kadhim Souliman and Dirk T Deleu and Kamran Saadat and Wael Abdulrahman Al Mahmeed and Sharif Bakir and Adel Wasif and Azan Ben Brek and Nooshin Mohd Bazargani and Ahmed Abdel Aziz and Rajvir Singh and Iman Hatou and Hisham A. Mahmoud and Jassim Al suwaidi}, journal={Angiology}, year={2009}, volume={60 3}, pages={329-34} }