AnkB, a Periplasmic Ankyrin-Like Protein inPseudomonas aeruginosa, Is Required for Optimal Catalase B (KatB) Activity and Resistance to Hydrogen Peroxide

@article{Howell2000AnkBAP,
  title={AnkB, a Periplasmic Ankyrin-Like Protein inPseudomonas aeruginosa, Is Required for Optimal Catalase B (KatB) Activity and Resistance to Hydrogen Peroxide},
  author={M. Howell and E. Alsabbagh and J. F. Ma and U. Ochsner and M. Klotz and T. Beveridge and K. Blumenthal and E. Niederhoffer and R. Morris and D. Needham and G. E. Dean and M. A. Wani and D. Hassett},
  journal={Journal of Bacteriology},
  year={2000},
  volume={182},
  pages={4545 - 4556}
}
ABSTRACT In this study, we have cloned the ankB gene, encoding an ankyrin-like protein in Pseudomonas aeruginosa. TheankB gene is composed of 549 bp encoding a protein of 183 amino acids that possesses four 33-amino-acid ankyrin repeats that are a hallmark of erythrocyte and brain ankyrins. The location ofankB is 57 bp downstream of katB, encoding a hydrogen peroxide-inducible catalase, KatB. Monomeric AnkB is a 19.4-kDa protein with a pI of 5.5 that possesses 22 primarily hydrophobic amino… Expand
Role for the Ankyrin eukaryotic-like genes of Legionella pneumophila in parasitism of protozoan hosts and human macrophages.
TLDR
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TLDR
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A major catalase gene (katB) that is required for resistance to H2O2- and phagocyte-mediated killing in Ed. Expand
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