Anisotropy, fiber curvature, and bath loading effects on activation in thin and thick cardiac tissue preparations: simulations in a three-dimensional bidomain model.

@article{Henriquez1996AnisotropyFC,
  title={Anisotropy, fiber curvature, and bath loading effects on activation in thin and thick cardiac tissue preparations: simulations in a three-dimensional bidomain model.},
  author={Craig S. Henriquez and A L Muzikant and C K Smoak},
  journal={Journal of cardiovascular electrophysiology},
  year={1996},
  volume={7 5},
  pages={424-44}
}
INTRODUCTION A modeling study is presented to explore the effects of tissue conductivity, fiber orientation, and presence of an adjoining extracellular volume conductor on electrical conduction in cardiac muscle. Simulated results are compared with those of classical in vitro experiments on superfused thin layer preparations and on whole hearts. METHODS AND RESULTS The tissue is modeled as a three-dimensional bidomain block adjoining an isotropic bath. In the thin layer model, the fibers are… CONTINUE READING

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