Anisotropic rotation in nucleic acid fragments: significance for determination of structures from NMR data

  title={Anisotropic rotation in nucleic acid fragments: significance for determination of structures from NMR data},
  author={Andrew J. Birchall and Andrew N. Lane},
  journal={European Biophysics Journal},
Proton-proton relaxation rate constants depend on the angle between the internuclear vector and the principal axis of rotation in symmetric top molecules. It is possible to determine to rotational correlation times of the equivalent ellipsoid for DNA fragments from a knowledge of the axial ratio and the cross-relaxation rate constant for the cytosine H6-H5 vectors. The cross-relaxation rate constants for the cytosine H6-H5 vectors have been measured in the 14-base-pair sequence dGCTGTTGACAATTA… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-9 of 9 extracted citations


Publications referenced by this paper.
Showing 1-10 of 19 references

Lane AN (1990) 31p NMR relaxation measurements of the phosphate backbone of a double-stranded hexanucleotide in solution: determination of the chemical shift anisotropy

M JForster
Eur J Biophys • 1979
View 4 Excerpts
Highly Influenced

deoxyriboses in the DNA hexamer d(CGTACG)z by 1H NMR

AN Lane, J-F Lefvre, O Jardetzky
Eur Biophys J • 1986
View 3 Excerpts
Highly Influenced

Characterisation of the overall and internal dynamics of short oligonucleotides by depolarised dynamic light scattering and NMR relaxation measurements

Freeman, W San Francisoc Eimer, JR Williamson, SG Boxer, R Pecora
Biochemistry • 1990

The determination of the conformational properties of nucleic acids in solution from NMR data

AN Lane, MJ Forster
Biochim Biophys Acta • 1990

Determination of internal dynamics of deoxyriboses in the DNA hexamer d ( CGTACG ) z by 1 H NMR

AN Lane, O Jardetzky
Eur Biophys J • 1989

COMATOSE, a method for constained refinement of macromolecular structure based on twodimensional nuclear Overhauser enhancement spectra

BA Borgias, TL James
J Magn Reson • 1988
View 1 Excerpt

Dynamics of proteins and nucleic acids

JA McCammon, SC Harvey
View 1 Excerpt

Nuclear magnetic resonance studies and distance geometry studies of DNA structures in solution

D JPatel, L Shapiro, D Hare
Q Rev Biophys • 1987

Similar Papers

Loading similar papers…