Anisomycin superinduces annexin V mRNA expression through the ERK1/2 but not the p38 MAP kinase pathway.

@article{Konishi2004AnisomycinSA,
  title={Anisomycin superinduces annexin V mRNA expression through the ERK1/2 but not the p38 MAP kinase pathway.},
  author={Yoshitomo Konishi and Hirokazu Sato and Toshinobu Tanaka},
  journal={Biochemical and biophysical research communications},
  year={2004},
  volume={313 4},
  pages={
          977-83
        }
}
Annexin V is a Ca(2+)-dependent phospholipid-binding protein belonging to the annexin family whose regulation is currently not well understood. In this study, we utilized anisomycin, a protein synthesis inhibitor that activates MAP kinases (MAPKs), to examine the role of MAPKs in annexin V expression in the MCAS ovarian carcinoma cell line. A one-step real-time TaqMan-based reverse transcriptase-PCR method was developed to quantify annexin V mRNA expression. We found that annexin V was induced… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Nanotopographical Control of Stem Cell Differentiation

Journal of tissue engineering • 2010
View 7 Excerpts
Highly Influenced

MAPK mediates Hsp25 signaling in incisor development

Histochemistry and Cell Biology • 2009
View 1 Excerpt

Similar Papers

Loading similar papers…