Anin vivo analysis of transcriptional elements in the mouse α-myosin heavy chain gene promoter

Abstract

During development in the murine ventricle, there is a switch in myosin heavy chain gene (MyHC) transcription. The β-MyHC is expressed in the ventricles during foetal development, but is shut down at or around birth, at which time α-MyHC transcription is activated. This antithetical switch is thought to be mediated by circulating levels of thyroid hormone… (More)
DOI: 10.1007/BF01973758

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