Animal tests of anxiety.

@article{File2005AnimalTO,
  title={Animal tests of anxiety.},
  author={Sandra E. File and Arnold S Lippa and Bernard Beer and Morgen T Lippa},
  journal={Current protocols in pharmacology},
  year={2005},
  volume={Chapter 5},
  pages={Unit 5.38}
}
Animal tests of anxiety are used to screen novel compounds for anxiolytic or anxiogenic activity, to investigate the neurobiology of anxiety, and to assess the impact of other occurrences such as exposure to predator odors or early rearing experiences. This unit presents protocols for the most commonly used animal tests of anxiety. The Geller-Seifter conflict test, the social interaction test, light/dark exploration, the elevated plus-maze, defensive burying, and the thirsty rat conflict. The… CONTINUE READING

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