Animal models of multiple sclerosis.

  title={Animal models of multiple sclerosis.},
  author={Roberto Furlan and Carmela Cuomo and Gianvito Martino},
  journal={Methods in molecular biology},
Since its first description, experimental autoimmune encephalomyelitis, originally designated experimental allergic encephalitis (EAE), has been proposed as animal model to investigate pathogenetic hypotheses and test new treatments in the field of central nervous system inflammation and demyelination, which has become, in the last 30 years, the most popular animal model of multiple sclerosis (MS). This experimental disease can be obtained in all mammals tested so far, including nonhuman… CONTINUE READING
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