Animal models of limbic epilepsies: what can they tell us?

  title={Animal models of limbic epilepsies: what can they tell us?},
  author={Douglas A. Coulter and Dan McIntyre and Wolfgang L{\"o}scher},
  journal={Brain pathology},
  volume={12 2},
In this review, we have provided an overview of the implementation and characteristics of some of the most prevalent models of temporal lobe epilepsy in use in laboratories around the world today. These include spontaneously seizing models with status epilepticus as the initial precipitating injury (including the kainate, pilocarpine, and electrical stimulation models), kindling, and models of drug refractoriness. These models share various features with one another, and also differ in many… CONTINUE READING


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