Animal models of epilepsy: use and limitations

  title={Animal models of epilepsy: use and limitations},
  author={Ludmyla Kandratavicius and Priscila Alves Balista and Cleiton Lopes-Aguiar and Rafael N Ruggiero and Eduardo H Umeoka and Norberto Garcia-Cairasco and Lezio S Bueno-Junior and Joao Pereira Leite},
  booktitle={Neuropsychiatric disease and treatment},
Epilepsy is a chronic neurological condition characterized by recurrent seizures that affects millions of people worldwide. Comprehension of the complex mechanisms underlying epileptogenesis and seizure generation in temporal lobe epilepsy and other forms of epilepsy cannot be fully acquired in clinical studies with humans. As a result, the use of appropriate animal models is essential. Some of these models replicate the natural history of symptomatic focal epilepsy with an initial… CONTINUE READING
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Models of seizures and epilepsy

  • A Pitkänen, PA Schwartzkroin, SL. Moshé
  • Amsterdam: Elsevier Academic;
  • 2006
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