Animal models of atopic dermatitis.

@article{Jin2009AnimalMO,
  title={Animal models of atopic dermatitis.},
  author={Haoli Jin and Rui He and Michiko K Oyoshi and Raif S Geha},
  journal={The Journal of investigative dermatology},
  year={2009},
  volume={129 1},
  pages={31-40}
}
Atopic dermatitis (AD) is characterized by allergic skin inflammation. A hallmark of AD is dry itchy skin due, at least in part, to defects in skin genes that are important for maintaining barrier function. The pathogenesis of AD remains incompletely understood. Since the description of the Nc/Nga mouse as a spontaneously occurring model of AD, a number of other mouse models of AD have been developed. They can be categorized into three groups: (1) models induced by epicutaneous application of… CONTINUE READING

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