Animal models of atopic dermatitis.

  title={Animal models of atopic dermatitis.},
  author={Haoli Jin and Rui He and Michiko K Oyoshi and Raif S Geha},
  journal={The Journal of investigative dermatology},
  volume={129 1},
Atopic dermatitis (AD) is characterized by allergic skin inflammation. A hallmark of AD is dry itchy skin due, at least in part, to defects in skin genes that are important for maintaining barrier function. The pathogenesis of AD remains incompletely understood. Since the description of the Nc/Nga mouse as a spontaneously occurring model of AD, a number of other mouse models of AD have been developed. They can be categorized into three groups: (1) models induced by epicutaneous application of… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-10 of 124 extracted citations

IL-17A as an inducer for Th2 immune responses in murine atopic dermatitis models.

The Journal of investigative dermatology • 2014
View 4 Excerpts
Highly Influenced


Publications referenced by this paper.
Showing 1-10 of 70 references

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

The Journal of experimental medicine • 2005
View 4 Excerpts
Highly Influenced

Atopic dermatitis.

View 4 Excerpts
Highly Influenced

Immune mechanisms leading to atopic dermatitis.

The Journal of allergy and clinical immunology • 2003
View 4 Excerpts
Highly Influenced

Association of the single-nucleotide polymorphism and haplotype of the interleukin 18 gene with atopic dermatitis in Koreans.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology • 2007
View 1 Excerpt

Epicutaneous antigen exposure induces a Th17 response that drives airway inflammation after inhalation challenge.

Proceedings of the National Academy of Sciences of the United States of America • 2007
View 2 Excerpts

Similar Papers

Loading similar papers…