Animal models of arrhythmia: classic electrophysiology to genetically modified large animals

@article{Clauss2019AnimalMO,
  title={Animal models of arrhythmia: classic electrophysiology to genetically modified large animals},
  author={Sebastian Clauss and Christina Bleyer and Dominik Christian Sch{\"u}ttler and Philipp Tomsits and Simone Renner and Nikolai Klymiuk and Reza Wakili and Steffen Massberg and Eckhard Wolf and Stefan K{\"a}{\"a}b},
  journal={Nature Reviews Cardiology},
  year={2019},
  pages={1-19}
}
Arrhythmias are common and contribute substantially to cardiovascular morbidity and mortality. The underlying pathophysiology of arrhythmias is complex and remains incompletely understood, which explains why mostly only symptomatic therapy is available. The evaluation of the complex interplay between various cell types in the heart, including cardiomyocytes from the conduction system and the working myocardium, fibroblasts and cardiac immune cells, remains a major challenge in arrhythmia… CONTINUE READING
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