Animal models of anorexia and cachexia.

@article{DeBoer2009AnimalMO,
  title={Animal models of anorexia and cachexia.},
  author={Mark D DeBoer},
  journal={Expert opinion on drug discovery},
  year={2009},
  volume={4 11},
  pages={
          1145-1155
        }
}
BACKGROUND: Cachexia is a devastating syndrome of body wasting that worsens quality of life and survival for patients suffering from diseases such as cancer, chronic kidney disease and chronic heart failure. Successful treatments have been elusive in humans, leaving a clear need for the development of new treatment compounds. Animal models of cachexia are able to recapitulate the clinical findings from human disease and have provided a much-needed means of testing the efficacy of prospective… CONTINUE READING

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