Animal models in overactive bladder research.

@article{Parsons2011AnimalMI,
  title={Animal models in overactive bladder research.},
  author={Brian Andrew Parsons and Marcus J Drake},
  journal={Handbook of experimental pharmacology},
  year={2011},
  volume={202},
  pages={15-43}
}
Overactive bladder syndrome (OAB) is a symptom-based diagnosis characterised by the presence of urinary urgency. It is highly prevalent and overlaps with the presence of bladder contractions during urine storage, which characterises the urodynamic diagnosis of detrusor overactivity. Animal models are needed to understand the pathophysiology of OAB, but the subjective nature of the symptom complex means that interpretation of the findings in animals requires caution. Because urinary urgency… CONTINUE READING

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