Animal models for the study of hepatic fibrosis.

@article{Starkel2011AnimalMF,
  title={Animal models for the study of hepatic fibrosis.},
  author={Peter Starkel and Isabelle A Leclercq},
  journal={Best practice & research. Clinical gastroenterology},
  year={2011},
  volume={25 2},
  pages={319-33}
}
Animal models are being used for several decades to study fibrogenesis and to evaluate the anti-fibrotic potential of therapies and strategies. Although immensely valuable for our understanding of pathophysiological processes, they remain models and none of them reproduces a human disease. Each model (meaning stimulus, design, strain and species) displays specific characteristics in the nature of the pathogenesis, the topography and the evolution of fibrosis. We review here the most used as… CONTINUE READING

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