Animal models for the study of antidepressant activity.


Three behavioral paradigms are presented for the study of the mechanism of action of antidepressant treatments and for the screening of new antidepressant drugs. The first model (acute escape deficit) exploits the decreased ability of a rat exposed to an unavoidable stress to avoid a noxious stimulus, and it allows us to evaluate the preventive activity of… (More)


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@article{Gambarana2001AnimalMF, title={Animal models for the study of antidepressant activity.}, author={Carla Gambarana and Simona Scheggi and Alessandro Tagliamonte and Paola Tolu and M. G. De Montis}, journal={Brain research. Brain research protocols}, year={2001}, volume={7 1}, pages={11-20} }