Animal models for fracture treatment in osteoporosis

  title={Animal models for fracture treatment in osteoporosis},
  author={Marcus Egermann and Joerg Goldhahn and Erich Schneider},
  journal={Osteoporosis International},
Demographic changes in the age structure of occidental populations are giving rise to osteoporosis and associated fractures, which are becoming a major public health burden. Various animal models have been established and used to investigate the pathogenesis of osteoporosis and to facilitate the preclinical testing of new treatment options such as antiresorptive drugs. Although osteoporosis can be induced in animals, spontaneous fractures without adequate trauma were only found in nonhuman… CONTINUE READING