Animal models for cartilage regeneration and repair.

  title={Animal models for cartilage regeneration and repair.},
  author={Constance R. Chu and Michal Szczodry and Stephen Bruno},
  journal={Tissue engineering. Part B, Reviews},
  volume={16 1},
Articular cartilage injury and degeneration are leading causes of disability. Animal studies are critically important to developing effective treatments for cartilage injuries. This review focuses on the use of animal models for the study of the repair and regeneration of focal cartilage defects. Animals commonly used in cartilage repair studies include murine, lapine, canine, caprine, porcine, and equine models. There are advantages and disadvantages to each model. Small animal rodent and… CONTINUE READING

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