Expression of E. coli RecA targeted to mitochondria of human cells.
- BiologyMutation research
Rewriting the information in DNA: RNA editing in kinetoplastids and myxomycetes.
- BiologyCurrent opinion in microbiology
Mitochondria, spermatogenesis, and male infertility - an update.
Mitochondrial DNA: Diversity Analysis and Possible Pitfalls
This work has shown that mitochondria represent relics of an α-proteobacterium that integrated into a thus far poorly understood host cell to constitute a primordial, complex eukaryotic cell and that the latter can be used to infer sister group relationships.
Variable Number Tandem Repeats in the Mitochondrial DNA of Lentinula edodes
Using the variations in VNTRs as a mitochondrial marker and the A mating type as a nuclear type marker, it is demonstrated that one of the two nuclei in the donor dikaryon preferentially enters into the monokaryotic cytoplasm to establish a new dkaryon which still retains the mitochondria of themonokaryon in the individual mating.
Maintenance of human rearranged mitochondrial DNAs in long-term cultured transmitochondrial cell lines.
- BiologyMolecular biology of the cell
In cells containing a mixture of monomeric and dimeric forms of a specific Delta-mtDNA, it was found that the mtDNA population shifted towards homoplasmic dimers, suggesting that there may be circumstances under which the cells favor molecules with multiple replication origins, independent of the size of the molecule.
The evolutionary processes of mitochondrial and chloroplast genomes differ from those of nuclear genomes
The variability occasionally observed in the inheritance mechanisms of cytoplasmic genomes reduces heritability and increases environmental components in phenotypic features and, consequently, decreases the potential for adaptive evolution.
Direct evidence for homologous recombination in mussel (Mytilus galloprovincialis) mitochondrial DNA.
- BiologyMolecular biology and evolution
It is suggested that animal mtDNA molecules may recombine regularly and that the extent to which this generates new haplotypes may depend only on the frequency of biparental inheritance of the mitochondrial genome.
Repetitive sequences in the lamprey mitochondrial DNA control region and speciation of Lethenteron.
Relationship between mitochondrial gene rearrangements and stability of the origin of light strand replication
Within amphibians there are stable and unstable phylogenetic groups regarding mitochondrial gene order, and several species did not present the 5-GCCGG-3 motif reported to be necessary for efficient mitochondrial DNA replication.
SHOWING 1-10 OF 13 REFERENCES
Molecular characterization of a repeat element causing large-scale size variation in the mitochondrial DNA of the sea scallop Placopecten magellanicus.
- BiologyMolecular biology and evolution
The structural properties of the repeat element and its organization in an array of repeats may be important in explaining the generation and maintenance of large-scale mitochondrial DNA size variation observed in many animal species.
Molecular mechanisms in genetic recombination.
- Biology, ChemistryAnnual review of biochemistry
Physical evidence for the Existence of the Holliday Recombination Intermediate and the Proposal of Meselson and Radding's Interwrapping Model are cited.
Age-related human mtDNA deletions: a heterogeneous set of deletions arising at a single pair of directly repeated sequences.
- BiologyAmerican journal of human genetics
Class B deletions offer a new approach for studying the accumulation of mtDNA deletions, thereby providing insight into the independent somatic origin of mutated mtDNA molecules, both in aging and in mitochondrial diseases.
Animal mitochondrial DNA: structure and evolution.
- BiologyInternational review of cytology
Recent appearance and molecular characterization of mitochondrial DNA deletions within a defined nematode pedigree.
The results indicate that the occurrence and selection of novel animal mitochondrial genomes can now be studied in this experimentally manipulable nematode system.
Absence of extensive recombination between inter- and intraspecies mitochondrial DNA in mammalian cells.
- BiologyExperimental cell research
EVOLUTION OF ANIMAL MITOCHONDRIAL DNA: RELEVANCE FOR POPULATION BIOLOGY AND SYSTEMATICS
This work focuses on molecular aspects of animal mtDNA that are especially relevant to its use in evolutionary studies, and considers the form and frequency of three types of change in mtDNA: base substitution, length variation, and sequence rearrangement.
Repeated sequence sets in mitochondrial DNA molecules of root knot nematodes (Meloidogyne): nucleotide sequences, genome location and potential for host-race identification.
- BiologyNucleic acids research
Data from Southern hybridization experiments indicate that 102 ntp and 63 ntp repeats occur in the mtDNAs of three, two and two races of M.javanica and the different host races ofM.arenaria, and nucleotide sequences of the M.incognita Race-3 102 nTP repeat are sufficient to distinguish the differenthost races of each species.
Molecular population genetics of mtDNA size variation in crickets.
In populations where hybridization between the two species has occurred, the frequencies of size classes and cytoplasmic genotypes in each species' distinct mtDNA lineage were shifted in a manner suggesting nuclear-cytoplasmsic interactions.
Length heteroplasmy of sturgeon mitochondrial DNA: an illegitimate elongation model.
A model for the replicative origin of length differences, involving a competitive equilibrium between the heavy strand and the D-loop strand, is proposed and suggests that frequent misalignment in the repeat region prior to elongation can explain both the polymorphism and heteroplasmy in this species.