Animal domestication in the era of ancient genomics

  title={Animal domestication in the era of ancient genomics},
  author={Laurent Alain François Frantz and Daniel G. Bradley and Greger Larson and Ludovic Orlando},
  journal={Nature Reviews Genetics},
  pages={449 - 460}
The domestication of animals led to a major shift in human subsistence patterns, from a hunter–gatherer to a sedentary agricultural lifestyle, which ultimately resulted in the development of complex societies. Over the past 15,000 years, the phenotype and genotype of multiple animal species, such as dogs, pigs, sheep, goats, cattle and horses, have been substantially altered during their adaptation to the human niche. Recent methodological innovations, such as improved ancient DNA extraction… 
The Fox Domestication Experiment and Dog Evolution: A View Based on Modern Molecular, Genetic, and Archaeological Data
There are parallels in behavior change and its molecular genetic basis between domesticated foxes and dogs, with a special focus on the so-called “ancient” breeds.
Dog domestication and the dual dispersal of people and dogs into the Americas
Comparing population genetic results of humans and dogs from Siberia, Beringia, and North America shows that there is a close correlation in the movement and divergences of their respective lineages, and suggests that dogs were domesticated in Siberia by ∼23,000 y ago, possibly while both people and wolves were isolated during the harsh climate of the Last Glacial Maximum.
Ancient DNA reveals the lost domestication history of South American camelids in Northern Chile and across the Andes
The study of South American camelids and their domestication is a highly debated topic in zooarchaeology. Identifying the domestic species (alpaca and llama) in archaeological sites based solely on
Large-scale genomic analysis reveals the genetic cost of chicken domestication
A new landscape of demographic history and genomic changes associated with chicken domestication is revealed and insight is provided into the evolutionary genomic profiles of domesticated animals managed under modern human selection.
Ancient Faunal History Revealed by Interdisciplinary Biomolecular Approaches
This review will approach how biomolecules have been implemented in a broad variety of topics and species, as well as how their future use has the potential to offer an enhanced understanding of drivers of past faunal diversity on Earth.
Domestic chicken diversity: Origin, distribution, and adaptation.
The role of human and natural selection in shaping the diversity of the species is highlighted and a few examples of knowledge gaps are provided that may be the focus of future research.
Human adaptation, demography, and cattle domestication: an overview of the complexity of lactase persistence in Africa.
This review summarizes recent advances in the understanding of the genetic basis and evolutionary history of lactase persistence, as well as the factors that influenced the origin and spread of pastoralism in Africa.
Runs of homozygosity in Swiss goats reveal genetic changes associated with domestication and modern selection
The information from ROH islands using WGS data is suitable for the analysis of signatures of selection and allowed the detection of protein coding variants that may have conferred beneficial phenotypes during goat domestication.
Whole-Genome Resequencing of Worldwide Wild and Domestic Sheep Elucidates Genetic Diversity, Introgression, and Agronomically Important Loci
A comprehensive genome resource for wild ovine species, landraces and improved breeds of domestic sheep, comprising high-coverage whole genomes of 810 samples from 7 wild species and 158 diverse domestic populations, finds two main waves of migrations across the Eurasian Steppe and the Iranian Plateau in the Early and Late Bronze Ages.


Ancient goat genomes reveal mosaic domestication in the Fertile Crescent
It is demonstrated that multiple divergent ancient wild goat sources were domesticated in a dispersed process that resulted in genetically and geographically distinct Neolithic goat populations, echoing contemporaneous human divergence across the region.
Ancient genomic changes associated with domestication of the horse
Early domestication selection patterns supporting the neural crest hypothesis are found, which provides a unified developmental origin for common domestic traits and reveals that Iron Age Scythian steppe nomads implemented breeding strategies involving no detectable inbreeding and selection for coat-color variation and robust forelimbs.
Prehistoric genomes reveal the genetic foundation and cost of horse domestication
Significance The domestication of the horse revolutionized warfare, trade, and the exchange of people and ideas. This at least 5,500-y-long process, which ultimately transformed wild horses into the
Establishing the validity of domestication genes using DNA from ancient chickens
Estimating genetic variability in ancient European chickens over the past 2,000 years shows that a mutation thought to be crucial during chicken domestication was not subjected to strong human-mediated selection until much later in time, demonstrating that the ubiquity of mutations does not necessarily imply ancient origins.
Unlocking the origins and biology of domestic animals using ancient DNA and paleogenomics
This review shows how studies of ancient DNA from domestic animals and their wild progenitors and congeners have shed new light on the genetic origins of domesticates, and on the process of domestication itself.
Ancient pigs reveal a near-complete genomic turnover following their introduction to Europe
While pigs were not independently domesticated in Europe, the vast majority of human-mediated selection over the past 5,000 y focused on the genomic fraction derived from the European wild boars, and not on the fraction that was selected by early Neolithic farmers over the first 2,500 y of the domestication process.
Multiple maternal origins and weak phylogeographic structure in domestic goats
It is suggested that goats and other farm animals have multiple maternal origins with a possible center of origin in Asia, as well as in the Fertile Crescent, and goat populations are surprisingly less genetically structured than cattle populations.
The Genetic Architecture of Domestication in Animals
  • D. Wright
  • Biology
    Bioinformatics and biology insights
  • 2015
This review focuses on what is currently known about the genetic architecture of domesticated animal species, if genes of large effect are prevalent in driving the domestication phenotype, and whether pleiotropy can explain the loci underpinning these diverse traits being colocated.
Genomic and archaeological evidence suggest a dual origin of domestic dogs
Results suggest that dogs may have been domesticated independently in Eastern and Western Eurasia from distinct wolf populations, and East Eurasian dogs were then possibly transported to Europe with people, where they partially replaced European Paleolithic dogs.