Animal antimicrobial peptides: an overview.

@article{Andreu1998AnimalAP,
  title={Animal antimicrobial peptides: an overview.},
  author={David Andreu and Luis Rivas},
  journal={Biopolymers},
  year={1998},
  volume={47 6},
  pages={
          415-33
        }
}
Antibiotic peptides are a key component of the innate immune systems of most multicellular organisms. Despite broad divergences in sequence and taxonomy, most antibiotic peptides share a common mechanism of action, i.e., membrane permeabilization of the pathogen. This review provides a general introduction to the subject, with emphasis on aspects such as structural types, post-translational modifications, mode of action or mechanisms of resistance. Some of these questions are treated in depth… 
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An overview of the general mechanism of action of antimicrobial peptides is presented and some of their additional properties, like antitumour activity, mitogenic activity, role in signal transduction pathways and adaptive immune response are discussed.
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The areas on antimicrobial peptides like source, properties, classification, mechanism of action, resistance and strategies for its applications are focused on.
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This review is focused on the functional and structural features of the naturally occurring antimicrobial peptides, and discusses their potential as therapeutics.
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The antimicrobial peptides isolated from marine invertebrates are discussed, and these peptides may provide the impetus for the development of novel strategies for the prevention of bacterial infections in animals.
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This review will summarize some of the recent developments that provide a better understanding of the mode of action of this unique family of antibacterial agents and give particular attention to the determinants of AMP-lipid bilayer interactions as well as to the different pore formation mechanisms.
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Overall characteristics of antimicrobial peptides are described based on the mechanism of action, classification of the peptides, report detection/screening methods and chemical/ biological production.
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TLDR
The sources of antimicrobial peptides, diversity in structural features, mode of action, production strategies and insight into the current data on their antimicrobial activity are reviewed followed by a brief comment on the peptides that have entered clinical trials.
Insect inducible antimicrobial peptides and their applications.
TLDR
The insect innate immune system with emphasis on inducible antimicrobial peptide properties against microbial invaders has been discussed.
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